While the exact cause of Hodgkin lymphoma may not be known, several factors make increase the risk of developing the disease. Hodgkin lymphoma develops in lymphocytes, a type of white blood cell.

General

Gender: Men have a slightly greater chance of developing the disease than women.

Age: Adults in their 20s and early 30s and those over age 55 are at an increased risk for developing Hodgkin lymphoma.

Body

Epstein-Barr virus (EBV): Known for causing "mono" in young adults, EBV may be associated with certain cancers, including lymphomas.

Compromised immune system: Having a compromised immune system from HIV/AIDS, or from immunosuppressants to prevent organ transplant rejection, may increase the risk for developing Hodgkin lymphoma.

Genetics

Family history: Having a parent or sibling with the disease may increase the risk. However, the American Cancer Society reports that only 5 percent of cases are found to have a family link.

Learn more about genetic testing

Lifestyle

Geography: Hodgkin lymphoma is most common in North America and northern Europe.

Socioeconomic status: Hodgkin lymphoma is more common in individuals with a higher socioeconomic background.

Next topic: What are the symptoms of Hodgkin lymphoma?